WebJan 5, 2005 · BACKGROUND. The authors evaluated serum levels of folate, homocysteine, and vitamin B 12 in patients with head and neck squamous cell carcinoma (HNSCC) and in patients with laryngeal leukoplakia, a well known preneoplastic lesion.. METHODS. One hundred forty-four consecutive, untreated patients with HNSCC and 40 consecutive, … WebFour biomarkers are commonly employed to diagnose B12 deficiency: vitamin B12 (B12), holotranscobalamin (HoloTC), methylmalonic acid (MMA), and homocysteine (Hcy). 4cB12, a combined index of the B12 status, has been suggested to improve the recognition of B12 deficiency. We aimed to evaluate the four different markers for detecting B12 deficiency, …
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