WebMar 4, 2010 · The extent of OVA-specific T-cell proliferation was also determined using a mAb (KJ1-26) specifically reacting with the TCR expressed by CD4 + T cells of DO11.10 mice. 32 The number of KJ1-26 + cells was approximately 2 times lower in spleens of OVA-stimulated IVIg-treated mice compared with OVA-stimulated control mice (Figure 2B), in … WebAug 1, 1999 · Abstract. The majority of clonotypic CD4 + T cells in the intestinal lamina propria of DO11.10 TCR transgenic mice have an activated/memory phenotype and produce effector cytokines despite the absence of prior exposure to ovalbumin (OVA), the transgene-specific antigen. A small number of splenic T cells have a similar phenotype. Clonotypic …
Tolerogenic Immunomodulation by PEGylated Antigenic Peptides …
WebJun 25, 2024 · We found, that after a single OVA injection DO11.10 transgenic T cells did not respond with proliferation to IL-2, poorly to OVA peptide and much lower than endogenous non-anergized T cells to stimulation with CD3 and CD3/CD28 antibodies (Figures 5B, C). To further test whether a second OVA injection would promote the maintenance of the … WebTCR DO11.10 Antibodies Antibodies that detect TCR DO11.10 can be used in several scientific applications, including Flow Cytometry, ELISA and Immunohistochemistry. … grocery stores in hazlehurst ms
MIP-1α and MIP-1β differentially mediate mucosal and …
WebMay 8, 2024 · EG7-derived tumors were established via subcutaneous injection of 5 × 10 6 EG7-hSLAMF7 cells into the hind flanks of C57BL/6 mice ... we enumerated tumor-infiltrating and splenic OVA-specific CD8 + T cells from EG7-hSLAMF7–bearing mice. The OVA-tet + CD8 + T-cell population was increased 3.6-fold and 3.5-fold in tumors in the … WebDec 30, 2016 · BALB/c mice, adoptively transferred with OVA-specific T cells from DO11.10 mice, were immunized intravenously with the indicated amounts of OVA and 10 μg LPS as adjuvant and analyzed 14 hr later (A–C) or with 2 mg OVA + 10 µg LPS and analyzed over time (D). IL-2 secretion of OVA-TCR + CD4 + T cells was analyzed using the IL-2 … WebE.G7-OVA [derivative of EL4] is a model system for studying major histocompatibility complex (MHC) class I restricted responses of cytotoxic T lymphocytes in mice. Product … file explorer event viewer