WebSalvage therapy in recurrent germ cell cancer: ifosfamide and cisplatin plus either vinblastine or etoposide. Ann Intern Med. 1988 Oct 1;109(7):540-6. link to original article PubMed; Loehrer PJ Sr, Gonin R, Nichols CR, Weathers T, Einhorn LH. Vinblastine plus ifosfamide plus cisplatin as initial salvage therapy in recurrent germ cell tumor. WebMore About GEMCITABINE-CISPLATIN. Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug. Important: The drug information on this …
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Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, and germ cell tumors. Because of its widespread use, the cure rate for testicular cancer has increased from 10% to 85… WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. Unfortunately, the mechanism for cisplatin ...
WebZytostatika: Cisplatin, Carboplatin, Oxaliplatin, Satraplatin Platinanaloga verursachen ebenfalls Querver-netzungen der DNA durch kovalente Bindung des Platinatoms an zwei Nukleinbasen. Die DNA kann sich während der Zellteilung nicht korrekt verdoppeln. Die Wirkung beruht also auf einer Hemmung der DNA-Replikation. WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose limiting. The laboratory observation that forced hydration and diuresis may prevent ...
Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), intravenous solution (1 mg/mL) Drug class: Alkylating agents. Medically reviewed by Drugs.com on Feb 16, 2024. Written by Cerner Multum. See more Cisplatin is used together with other cancer drugs to treat bladder cancer, testicular cancer, or ovarian cancer. Cisplatin may also be used for purposes not listed in this … See more You should not be treated with cisplatin if you are allergic to it. Tell your doctor if you have ever had: 1. prior treatment with cisplatin; 2. hearing … See more Cisplatin can affect your nervous system, increase your risk of bleeding or infection, or harm your kidneys. Call your doctor if you have a fever, mouth sores, cough, sore throat, unusual bleeding or bruising, hearing problems, … See more Cisplatin is given as an infusion into a vein. A healthcare provider will give you this injection. Cisplatin is sometimes given for 5 days in a row, … See more WebInterpretation: Gemcitabine and cisplatin plus immunotherapy showed promising efficacy and acceptable safety in patients with biliary tract cancer. Gemcitabine and cisplatin …
WebRegime der PEB-Gabe scheint hierbei besser abzuschneiden als das 3-Tage-Regime (Bokemeyer et al. 1998). Die höheren Spitzenkonzentrationen von Cisplatin mit 50 mg/m2 bei der Gabe über zwei Tage im Vergleich zu 20 mg/m2 über fünf Tage mit einer Odds Ratio 7,3 bzw. 5,1 scheinen hier den wesentlichen Einflussfaktor darzustellen (Brydoy et al ...
WebCisplatin is also sometimes used to treat head and neck cancer (including cancer of the mouth, lip, cheek, tongue, palate, throat, tonsils, and sinuses), lung cancer, cancer of the cervix and esophagus, brain tumors, malignant pleural mesothlioma (cancer in the lining of the chest or abdomen), and neuroblastoma (a cancer that begins in nerve cells and … black history tidbitsWebシスプラチン（英語: cisplatin 、略称:CDDP）は、白金 錯体に分類される抗悪性腫瘍剤（抗がん剤）。 シスプラチンの「シス」は、立体化学の用語のシスに由来する。 錯体の中心金属は白金、配位子はアンミンと塩化物イオンであり、物質名はシス-ジアミンジクロロ白金(II)（cis-diamminedichloro-platinum ... black history ticketsWebDec 12, 2024 · Other drugs will be given before this drug to help with this. This drug may lower the ability of the bone marrow to make blood cells that the body needs. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Some infections have been severe and even deadly. black history timeline 1600 2015WebDec 14, 2024 · Die JCOG1008-Studie, eine multizentrische Phase-II/III-Studie, prüfte daher die Nichtunterlegenheit der wöchentlichen Gabe von Cisplatin in der Dosierung 40 … black history tiesWebDec 1, 2024 · Weekly Low-Dose Versus Three-Weekly High-Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non-Nasopharyngeal Head and Neck … black history tik tokWebLocally advanced squamous cell carcinoma of the head and neck: Approaches combining chemotherapy and radiation therapy. … trial, weekly cisplatin as part of definitive chemoradiation had noninferior locoregional control (LRC) and was better tolerated compared with bolus cisplatin . black history thurgood marshallWebTraduire. Français. Deutsch English Český Dansk Español Hrvatski Italiano Nederlands Polski Русский Svenska Turkce عربى বাংলা Suomi हिंदी Bahasa indonesia 日本語 한국어 മലയാളം मराठी Bahasa malay Norsk … gaming monitor officeworks